الفهرس 
Contents
Utility of corticosteroids in acute pediatric respiratory disordersOnly 14 pages are availabe for public view
 |  | from | 91 |  |  |
| | | from | 91 | | |
Abstract
Mechanical ventilation in pediatric patients may be complicated by post-extubation stridor leading to extubation failure and need for reintubation extending the duration of hospital stay and elevating the costs spent for that purpose. The current study aimed to evaluate the effectiveness of corticosteroids in prevention (IV dexamethasoen) and treatment (nebulized budesonide) of post-extubation stridor among the PICU patients. Patients included in the study were recruited from those admitted in PICU of MUCH and divided into two groups: the interventional group included 58 children and were given single dose of IV dexamethasone 6 hours before extubation while the control group included age and sex matched 58 children and were given the same volume of normal saline 6 hours befor extubation as the interventional group. Development of stridro was monitored in the two groups and the its score was recorded. Some patients data were recorded such as complete history, clinical examination and body mass index. Also, these laboratory data were recorded: serum hemoglobin level, serum k level and serum mg level. Patients aged below one month, those who received corticosteroids one week prior to extubation and those who underwent ear, nose and throat surgeries in this setting were excluded. Children who developed post-extubation stridor were subdivided into two subgroups: budesonide group was treated with both nebulized adrenaline and budesonide (interventional group), adrenaline group was treated with only nebulized adrenaline. The severity of stridor score was recorded. After data collection then analysis and use of the required statistical methods and illustration of these data in graphical tables and figures, it has been clear that corticosteroid reduced the incidence of post-extubation stridor and treated developed post-extubation stridor in the interventional groups compared with the control groups. We concluded that corticosteroids may be used prophylactically to prevent post-extubation stridor in children. Also adding budesonide to adrenaline in nebulization may be beneficial in treating post-extubation stridor in children. We recommend further studies to identify risk factors which may lead to post-extubation stridor and extubation failure.