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Abstract Background: The transversus abdominis plane (TAP) block involves the sensory nerve supply of the antero–lateral abdominal wall, where the T7–12 intercostal nerves, the ilioinguinal and iliohypogastric nerves, and the lateral cutaneous branches of the dorsal rami of L1 are blocked with an injection of local anesthetic between the internal oblique abdominal muscle and the transverse abdominal muscle. Aim of the Work: The aim of this study was to compare the post operative analgesic efficacy and safety of bilateral ultrasound-guided TAP block and systemic opioid analgesia after abdominal surgery in hepatic patients Patients and Methods: After approval of medical ethical committee of Faculty of Medicine, Ain Shams University, this prospective interventional clinical study was conducted on 60 hepatic patients, who were scheduled to undergo lower abdominal surgeries under general anesthesia. Patients were divided into 2 equal groups; first (A) was TAP group, second (B) was the opoid(pethedine) group.Results: There were statistically significant differences between the two groups as regards the incidence of postoperative nausea and vomiting with group (A) showing less incidence and also as regards the total 24 hours pethedine requirements with group (B) has 3 times more pethedine requirement than group (A).Conclusion: The use of TAP block as post operative analgesia in hepatic patients decrease the amount of postoperative opioids used and also associated with less incidence of postoperative nausea and vomiting which increases with the use of opioids. |