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العنوان
INCIDENCE & OUTCOME OF INVASIVE FUNGAL INFECTIONS IN PATIENTS WITH
FEBRILE NEUTROPENIA/
المؤلف
Hennawy,Fady Sobhy Kamal
هيئة الاعداد
باحث / فادي صبحي كمال حناوي
مشرف / مها محمد توفيق الزميتي
مشرف / نيفين نبيل مصطفى
مشرف / جيهان محمد كمال
مشرف / عماد عبد المحسن عبد الهادي
مشرف / رشا مجدي محمد سعيد
تاريخ النشر
2018
عدد الصفحات
233.p:
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب الباطني
تاريخ الإجازة
1/1/2018
مكان الإجازة
جامعة عين شمس - كلية الطب - Internal Medicine
الفهرس
Only 14 pages are availabe for public view

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from 233

Abstract

BACKGROUND: Invasive fungal infection (IFI) is a major cause morbidity and mortality among patients with hematological malignancies who receive chemotherapy or hematopoietic stem cell transplantation (HSCT). Thus, early diagnosis and treatment of these infections are of crucial importance. Certain factors have been identified as risk factors for IFI.
OBJECTIVES: Assessment of incidence and outcome of IFI in Egyptian patients with febrile neutropenia.
PATIENTS AND METHODS: 50 febrile neutropenia episodes were studied. Patients were all subjected to history taking, clinical examination and further investigations including imaging studies, Galactomannan and Mannan antigen assays, and patients were followed up for observing the outcome.
RESULTS: Our study found that hypertensive patients had significantly reduced LA function as measured by speckle tracking when compared to normotensive controls (P-value < 0.001). Also, many factors were associated with worse LA function in hypertensive patients as old age, high BMI, DM, LV diastolic dysfunction, high LV mass index, larger LA size, lower LA expansion index and higher systolic BP.
CONCLUSION: IFI incidence is affected by age, gender, primary diagnosis and severity of neutropenia, and IFI has a worse outcome compared to other causes of febrile neutropenia