![]() | Only 14 pages are availabe for public view |
Abstract In regularly transfused patients, iron overload is due to breakdown of red blood cell (7). Iron overload in patients with β- thalassemia major lead to alterations in the arterial structures and the thickness of the carotid arteries. In Addition, It was noted that Carotid Thickness is Positively Correlated with Age, Hemoglobin, ferritin and Atherogenic index of plasma (AIP) in these patients. As a result, coronary artery diseases (CAD) is a quite common cardiovascular complication in thalassemics. Patients on a regular transfusion regimen progressively develop clinical manifestations of iron overload associated with heart dysfunction and left ventricular failure if inadequately chelated. |