الفهرس 
Genetic susceptibility and group A StreptococcusOnly 14 pages are availabe for public view
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Abstract
Summary
Rheumatic fever is an illness that occurs following a
streptococcus infection and predominantly affects children.
Symptoms include fever, arthralgia, nausea and vomiting. RF can
cause long-lasting effects in the skin, joints, heart, and brain.
RF and RHD represent the main cause of death and disability
among school children in the developing countries. However, it is a
recurrent disease that can usually be prevented.
ASOT is a blood test to measure antibodies against streptolysin
O, a substance produced by GAS bacteria. The ASO antibody may be
found in the blood for weeks or months after the streptococcal
infection has gone away.
Ischaemia-modified albumin is a new marker for tissue
ischaemia . It has been proposed that reactive oxygen species
generated during ischaemia results in ischaemia-modified albumin
formation. Ischaemia-modified albumin is accepted as a marker of
oxidative stress. Recently, elevated ischaemia-modified albumin
levels have been reported in various clinical conditions such as
ischaemia, inflammation, and oxidative stress. Furthermore,
increased oxidative stress has been shown in acute rheumatic fever
and heart valve disease.
The aim of the work was to measure the level of ischemia
modified albumin in sera of families with a case of rheumatic
fever and / or rheumatic heart diseases whatever their presentation .
More over, the level of ischemia modified albumin may give us an.