الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Knee OA is one of the commonest joint disorders affecting the adult population worldwide. KOA prevalence increases with increasing age and is more common in women than in men. It can be defined as primary or secondary according to the presence or absence of risk factors including: repetitive knee injuries, previous knee surgery, and overuse.
Osteoarthritis diagnosis is clinical and radiological. Clinically OA is characterized by joint pain, tenderness, and mild to moderate joint effusion, limited movement, and short lasting morning stiffness. Plain x-ray is the most imaging used to confirm the clinical diagnosis and is characterized by joint space narrowing, osteophytes and sclerosis.
The aim of the work was to investigate the association between KOA, cardiovascular risk factors and the Framingham risk score in a group of Egyptian population.
The study included two groups, the patient group consisted of 30 KOA patients diagnosed according to the EULAR criteria, and patients were excluded if they had secondary KOA or were than less than 40 years of age. The other group consisted of 30 age and sex matched healthy adult as control.
Cardiovascular risk factors such as: smoking, level of physical activity, hypertension, Diabetes and cholesterol level were assessed in both groups and used to calculate the Framingham risk score.
We found a statistically significant difference between both groups as regard to the blood pressure, fasting blood sugar. KOA patient had a higher level of FBS and most of them were hypertensive on medication.
In conclusion KOA patients might be at an increased risk of developing cardiovascular diseases due to its association with some of the cardiovascular risk factors such as hypertension and DM, as well as due to the disability resulting from the disease it self.