الفهرس 
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Abstract
Vitamin D3 and adenosine monophosphate compounds have a great biological, industrial and coordination applications. A general survey of previous literature concerning the interaction of metal ions with the above compounds was given. The present work was aimed mainly to study the spectroscopic, stability and related thermodynamic parameters, structural, thermal, molar conductivity and biological properties of the above ligands with VO(II) metal ion and some amino acids such as isoleucine, threonine, proline, phenylalanine, lysine and glutamine.
The used theoretical concepts and experimental techniques were discussed. The outcome of the results can be summarized as the following:
1- The solid complexes have been prepared and characterized by IR, UVvis, elemental analysis CHN and 1H-NMR. The outcome of the results is: Vitamin D3 reacts with VO(II) and amino acids by molar ratio (1:1) (VD3 : metal ion ) and (1 : 1 : 1 ) (VD3 : metal ion : AA) respectively, which supported by elemental analysis. The IR and UV-vis spectra of the solid complexes indicate that vitamin D3 behaves as a as monodentate ligand and coordinates to the VO(II) metal ion via the hydroxyl oxygen atom. Adenosine monophosphate reacts with VO(II) and amino acids by molar ratio (1:1) (AMP : metal ion ) and (1 : 1 : 1 ) (AMP : metal ion : AA) respectively, which supported by elemental analysis. The IR and UV-vis spectra of the solid complexes indicate that adenosine monophosphate behaves as bidentate ligand and coordinates to the VO(II) metal ion via the two phosphate oxygen atoms.
2- Thermogravimetric analysis (TG) and differential thermo gravimetric analysis (DTG) of the representative complexes were carried out to identify their thermal stabilities structure; the results are summarized as the following: • At the first loss water of hydration, then loss of coordination water and finally decomposition of ligand. The final residue at the end is the corresponding metal oxide or carbide. 3- The thermodynamic parameters, the free energy change (ΔG*), the enthalpy change (ΔH*), activation energy (E*) and the entropy change (ΔS*), were calculated using Coats-Redfern and Horowitz-Metzeger methouds to determine whether the reaction is thermodynamically stable or not. The results show that the ΔG* values are positive for all metal complexes indicating a non-spontaneous process with thermodynamic stability. The positive ΔH* values postulate an endothermic nature of the formed complexes. The grater negative values of ΔS* reveal that most complexes are more ordered and have high stability. 4- Molar conductivities of the representative complexes are studied and the results are summarized as: • Molar conductance values for vitamin D3 and adenosine monophosphate complexes seem to be non-electrolytes also molar conductance values indicate that no ions are present outside the coordination sphere so the SO4-- ions may be exhibit inside the coordination sphere or absent. The obtained results were strongly matched with the elemental analysis data where SO4 ions are absence by addition of BaCl2.2H2O reagent to the solution of the complexes after decomposition using concentrated nitric acid.