الفهرس 
SYSTEMIC LUPUS ERYTHEMATOSUSOnly 14 pages are availabe for public view
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Abstract
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with a broad spectrum of clinical manifestations that predominantly affects young women during childbearing age. The disease onset of SLE can also occur in pediatric and older populations.
Patients and Method:
One hundred and fifty consecutive patients with SLE fulfilling the SLICC criteria for the classification of SLE (Petri et al., 2012) were included in the study. The patients were classified according to the age at disease onset.
Results:
This study was conducted on One hundred and fifty patients with SLE fulfilling the SLICC criteria for the classification of SLE (Petri et al., 2012). SLE patients were 141 females (94.00%) and 9 males (6.00%).
Conclusion:
- The age at onset of SLE influences its clinical and serological manifestations.
- JSLE patients have a more aggressive presentation and course than ASLE patients with a higher frequency of lupus nephritis, more cutaneous symptoms and hematological manifestations.
- JSLE patients have more severe disease activity with very high SLEDAI and SLICC damage scores.
- ASLE patients have more musculoskeletal manifestations