الفهرس | Only 14 pages are availabe for public view |
Abstract Neonatal septicaemia remains a major cause of morbidity and mortality in the neonatal period. The aim of this study is to evaluate the diagnostic value of resistin in neonatal sepsis, and to compare this adipocytokine with highly sensitive C-reactive protein (hs-CRP). In the present study, 60 infants with neonatal sepsis were consecutively enrolled from the Neonatal Intensive Care Unit (NICU) of ”Menoufia University Hospital” and ”Benha Children Hospital” from February to November 2017. In addition, 30 healthy neonates without history of prolonged rupture of the membranes served as a control group. The study protocol was approved by the Menoufia Faculty of Medicine Committee for Medical Research Ethics. Infants were thoroughly evaluated clinically. Resistin and routinely available sepsis markers, including hs-CRP, WBC, ANC, platelets count, I/T ratio, NLR ratio, and RDW were measured within 2 hours of NICU admission. Microbiological cultures were taken upon admission from potential sources of infection. Resistin and the other markers were also measured to all infants in the control group. The clinical condition was closely monitored and the primary outcome was in- hospital 30-day mortality. |