الفهرس 
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Abstract
Iron deficiency anemia is one of the most prevalent nutritional deficiencies in the world and the 12th most important risk factor for all mortality globally the prevalence of iron deficiency anemia in pregnancy in developing countries 35-75% (103).
Anemia during pregnancy need acute corrective measures because is associated with increased incidence of morbidity and mortality on mother and fetus . The primary objective of this study is to evaluate the effectiveness and safety of ferrous bis-glycinate fully reacted amino acid in comparison to ferrous glycine sulphate for treatment of iron deficiency anemia during pregnancy between 14-28weeks. Prospective randomized study done at Women Health Hospital – Assiut University started since January 2016 to June 2017 ,200 pregnant women was involved .
All women were anemic with HB less then 10gm/dl .They had variable complaints.They allocated to two treatment groups either group I (treated by ferrous bis-glycinate) or group II (treated by ferrous glyine sulphate).
All women were compared for age,parity,BMI,change in HB level and iron parameters 4 and 8 weeks after treatment,cord HB,gestational age at delivery, birth weight.
Ferrous bisglycinate causes significant increase in HB ,serum iron ,ferritin and improvement of TIBC compared to ferrous glycine sulphate , so its safe and effective for treatment of moderate iron deficiency anemia during pregnancy also it has better fetal outcome .
Conclusion
Oral iron (Ferrous bis glycinate) increases iron stores significantly and has tolerable adverse effects. Ferrous bis glycinate also increases Hb and produces less adverse effects than the oral iron (ferrous glycine sulphate) . Thus, ferrous bis glycinate could be considered as an effective for treatment and prevention of iron deficiency anemia during pregnancy