الفهرس 
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Abstract
Background: PCOS is the most common endocrine disorder among women between the ages of 18 and 44 and is thought to affect approximately 2% to 20% of this age group depending on how it is defined. It is one of the leading causes of poor fertility.
Aim of the Work: metformin role in helping conception to occur?, Metformin improve the receptivity of the endometrium of polycystic ovarian syndrome patients?
Patients and Methods: the present study included 85 patients from Ain Shams University outpatient gynecology and infertility clinic during the period from January 2018 till June 2018. The study included 85 anovulatory patients with PCOS who attend Ain Shams University Maternity Hospital outpatient infertility and Gynecology clinic.
Results: in the current study, metformin therapy leads to significant increase of endometrial thickness and had a significant effect on uterine RI and PI. On the endometrial level, endometrial and subendometrial R.I and P.I were significantly reduced after metformin treatment indicating better blood flow.
Conclusion: that endometrial vascularity was abnormally reduced in women with anovulatory PCOS compared to normally ovulating women. Metformin therapy improves endometrial vascularity in such a way that was more pronounced in women responding to treatment. In addition, it increases endometrial thickness and improved impedance observed in uterine artery flow observed in women with PCOS. Unfortunately, we could not predict ovulatory response through measurement of power Doppler indices of the endometrium and subendometrial regions.