الفهرس | Only 14 pages are availabe for public view |
Abstract This thesis divided into two parts, as follows: part One: Synthesis Of New 2-N-Substitutedamino-5-aryl-1,3-thiazoles As Antitumor Agents This section contains the manufacture of new thiazole derivatives, chemical structure of the new 1,3-thiazole derivatives has been demonstrated by chemical and spectral methods (IR, NMR and mass spectrometry). The biological activity of thiazole and carbazone derivatives, which were prepared as anti-cancer drugs against two different cancer cell lines (breast cancer cell line, liver cancer cell line). Part two: Synthesis and Biological Evaluation of Some Novel 2-Thiohydantoin Derivatives As Apoptosis Inducer This part contains the design, synthesis, and biological evaluation of new derivatives of thiohydantoin. |