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Abstract Wide varieties of lesions affecting the eyelid are encountered within routine ophthalmology practice. These lesions are numerous due to the unique anatomical features of the eyelid as the whole skin structures, appendages, muscle, modified glands, and conjunctival mucous membrane are represented in the eyelid. The eyelid contains different types of glands that clinically correlate with the development of eyelid cysts; sebaceous glands (Meibomian glands and glands of Zeis), aporcine glands (glands of Moll) and eccrine sweat glands. Various types of cysts can be identified in the eye lid, e.g; external and internal hordeolum, chalazion, sebaceous cyst, cyst of Zeis gland, epidermal inclusion cyst and hidrocystomas (apocrine and eccrine). Some other lesions can rarely present in the eyelid margin such as: intratarsal keratinous cysts, pseusocystic appearance of pleomorphic adenoma, tarsal dermoid cyst, trichilemmal Cyst, apocrine retention cysts chromhidrosis, and cystic variant of basal cell carcinoma. Some of these entities can present as recurrent chalazion and can only be differentiated from it by histopathology. |