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Abstract n The kidneys regulate the composition and volume of blood, remove metabolic wastes in the urine, and help control the acid/ base balance in the body. They activate vitamin D needed for calcium absorption and produce erythropoietin needed for red-blood-cell synthesis (NKDEP , 2015). Chronic kidney disease CKD is typically a progressive disease. It is defined as a reduction of kidney function to an estimated glomerular filtration rate (eGFR) of < 60 mL/min/1.73 m2 and/ or an evidence of kidney damage, including persistent albuminuria; defined as > 30 mg of urine albumin per gram of urine creatinine. Kidney failure is typically defined as an eGFR< 15 mL/min/1.73 m (NKDEP, 2015) |