الفهرس 
The Specific Role of Adipocyte Inflammatory SecretagoguesOnly 14 pages are availabe for public view
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Abstract
Obesity continues to be among the top health concerns across the globe .obesity is considered a disease of century(10). Obesity has important consequences for morbidity, disability and quality of life and entails a higher risk of developing type 2 diabetes, cardiovascular diseases, several common forms of cancer, osteoarthritis and other health problems (12). Non-alcoholic fatty liver disease (NAFLD) is considered ,most common cause of end stage Liver disorder needing liver transplantation worldwide especially in Western industrialized countries (3) , where the major risk factors for NAFLD, central obesity, type 2 diabetes mellitus, dyslipidemia, and metabolic syndrome are common (88). The term NAFLD includes a wide spectrum of conditions, from simple accumulation of fat (‗fatty liver‘ or steatosis) to steatohepatitis (NASH), fibrosis and cirrhosis with its clinical consequences like hepatocellular carcinoma (90). NAFLD is considered the hepatic presentation of metabolic syndrome. The association between thyroid dysfunction and NAFLD has increasingly become a focus of research. Previous studies propose that hypothyroidism might play a crucial role in the pathogenesis of NAFLD ,but findings from published studies on the relationship between hypothyroidism and NAFLD are still controversial. The outcome of the present study agree in many points with the findings of numerous publications that there is elevation in levels of TSH within the normal range in NAFLD group over Non-NAFLD group , as about 65% of NAFLD group reported elevated TSH level more than or equal 2.7 mIU/L but within normal range low than 4.2 mIU/L . Also FT4 results was within normal range 0.8-1.8 ng/dl with lower levels in NAFLD group than Non-NAFLD . Other thyroid function like thyroid antibodies (ANTI-TPO, Tg Ab ) ,ultrasound neck show no significant difference between NAFLD, Non-NAFLD groups within this study .