الفهرس 
Recommendations for Measurement of Serum MarkersOnly 14 pages are availabe for public view
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Abstract
Acute ST-segment myocardial infarction is one of the most important cardiovascular diseases that increase risk of morbidity and mortality. The primary goal in management of acute STEMI is reperfusion therapy with intravenous fibrinolysis or primary percutaneous intervention. Acute kidney injury is a frequent complication among patients who undergo primary percutaneous intervention shown to be associated with adverse outcomes. Many predictive risk scores were developed to estimate risk of CIN as: Mehran risk score developed by Mehran R et al, ACEF score developed by Andò et al and Novel risk prediction algorithm using computational tool proposed by Gurm et al. The present study aimed to evaluate CHA2DS2-VASC score as a predictor for contrast-induced nephropathy in patient with acute myocardial infarction treated with primary percutaneous coronary intervention. The present study was conducted at Cardiology Department, Tanta University Hospital. It was carried out on 100 adult patients of both genders diagnosed definitively with acute myocardial infarction treated with PPCI. The study population was subdivided into two groups: group I: those who developed contrast induced nephropathy 48h after primary PCI (36%) group II: those who not developed CIN 48h after PCI.(64%). This study show that CHA2DS2-VASC score can be used as a new, simple, and reliable tool to predict CIN in patients with acute myocardial infarction who underwent urgent primary percutaneous coronary intervention as CHADS2-VASC score >3 is independent risk factor for contrast induced nephropathy with 55.56%sensitivity and 98.44% specificity . According to the recurrent study, most of patients were developed contrast induced nephropathy post primary PCI were female, older in age, diabetic , hypertensive and presented with heart failure symptoms on admission (killip class III-IV) .