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Abstract hronic kidney disease (CKD) is a big social problem all over the world (Takashi and Fukumoto, 2016) characterized with loss of the kidney‘s function resulting in accumulation of metabolites in blood (Pinto et al., 2016). This leads to disturbance in fluids and electrolytes balance in the body, thereby causing serious health problems (Chen et al., 2016). CKD-mineral and bone disorder (CKD- MBD) is one of the major complications associated with CKD, manifested by abnormalities in bone and mineral metabolism or extra skeletal calcification. It is at least one of conditions that affect morbidity and mortality of patients with CKD (Moe. |