الفهرس | Only 14 pages are availabe for public view |
Abstract This study done to evaluate the effect of partial splenic artery embolization on blood elements in patients with hypersplenism due to chronic liver disease and to assess safety of the maneuver. The study include twenty five patient with thrombocytopenia due to hypersplenism caused by chronic liver disease. In follow up visit after one month, a full clinical assessment was done, CBC, liver functiontests and abdominal sonar or CT. The most common cause of chronic liver disease is HCV infection 16 patients (64%), bilharzial disease in 5 patients (20%) and mixed HCV and bilharzial infection in 4 patients (16%). Regarding the symptoms of the studied patients bleeding tendency was found in 25 patients (100%), while anemic manifestations was found in 15 patients (60%), hematemesis or melena was found in 14 patients (56%), abdominal enlargement was found in 6 patients (24%) and abdominal pain was found in 18 patients (72%). Partial splenic artery embolization can be done by one of two methods selective or non-selective and about 50 %of the vascular bed is occluded with Gelfoam or Ebosphere. Regarding the complications after the maneuver, Postembolization syndrome was the most common complication and occurred in all patients (100%). Ascites developed in 4 patients (16%). Portal vein thrombosis was developed in 2 patient (8%) Splenic abscess was developed in 1 patient (4%). No other complications has been reported. |