الفهرس 
Epidemiology
Squamous cell cancer:Only 14 pages are availabe for public view
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Abstract
Head and neck squamous cell cancer is a heterogeneous group of cancers, with a variable prognosis as well as a great impact on the patient’s quality of life. Despite advances in treatment,the mortality rate has not changed markedly over the last few
decades.Radiotherapy either alone or concurrently with chemotherapy is the main non-surgical treatment for squamous cell carcinoma of the head and neck.Radiation-induced xerostomia is the most commonly reported late side effect of radiotherapy to the head and neck.Over the last decade, a substantial change from conventional radiotherapy through 3D conformal RT
to IMRT was achieved.In IMRT, multiple shaped radiation beams are modulated to produce highly conformal dose distributions enabling delivery of higher doses to tumor tissue while limiting the dose delivered to defined normal structures.This is a prospective study carried out at Clinical Oncology Departments Tanta & Alex University
Hospitals, aimed to evaluate the dosimeteric distribution of IMRT in head and neck squamous cell cancer stage II-IVB as well as the clinical outcome of IMRT as regarding treatment response and toxicity profile. It included thirty patients who had head and neck cancer squamous cell cancer (stages II, III, IVA, IVB). All patients received concurrent chemoradiotherapy using IMRT followed by adjuvant treatment according to site and stage. For every patient 2 plans of IMRT and 3DCRT were generated and compared dosimetrically as regard to tumor coverage and dose to risk organs.