الفهرس 
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Abstract
Estrus cycle in bitches differs than in other domestic animals, characterized by long anestrum period in which inactivity of ovaries occur and its duration ranged from 4 to 12 months depending on breed, age, body weight and health status of bitches. Infertility problem is a common syndrome among bitches and its causes are numerous, but the apparent most frequent cause is the mating at incorrect time. So the purpose of this study was Shortening inter estrus interval by using dopamine agonist (cabergoline), GnRH agonist (Receptal) and gonadotropin (FSH and LH), comparing their efficacy in inducing fertile estrus in bitches and also evaluate the progesterone profiles in bitches following cycle induction with these drugs.Find the best accurate facilities for breeding management in bitches throughout comparing the clinical assessments as vaginal cytology, progesterone assay, and measurement of vaginal pH, vaginal endoscopy and ultrasonographic examination of ovaries, and use them in predicting the optimal time of breeding.Recording abnormalities in estrus cycle and try to treat them.¬
The clinical trial involved 21 bitches of mixed breeds that were divided equally into 3 groups for estrus induction.Their weights ranged from 10 – 20 Kg and their ages ranged from 2 – 5 years. They were housed from January to July months in 2018 in the Clinic of Veterinary Hospital in the Faculty of Veterinary Medicine, Zagazig University, Egypt. Moreover a total number.