Search In this Thesis
   Search In this Thesis  
العنوان
The Effect of Atorvastatin on ADMA Level
and Erectile Function in patients with
Vasculogenic Erectile Dysfunction /
المؤلف
Osman,Mohamed Ahmed Khalil.
هيئة الاعداد
باحث / Mohamed Ahmed Khalil Osman
مشرف / Adel Ahmed Halim Imam
مشرف / Mahmoud Abdel-Rahim Abdallah
تاريخ النشر
2019
عدد الصفحات
145p.:
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الأمراض الجلدية
تاريخ الإجازة
1/1/2019
مكان الإجازة
جامعة عين شمس - كلية الطب - الأمراض الجلدية والتناسلية وأمراض الذكورة
الفهرس
Only 14 pages are availabe for public view

from 145

from 145

Abstract

This study included two groups of subjects, first
group (study group) 30 patients aged 30-60 years old with
vasculogenic erectile dysfunction and the second group
(control group) included 30 healthy subjects. The aim of
our study is to demonstrate the effect of atorvastatin on
ADMA level and erectile function in patients with normal
or high LDL level vasculogenic erectile dysfunction.
We found that study group had significantly higher
serum levels of ADMA than the control patients. The
present study demonstrated that among men with
ultrasonographically documented vasculogenic ED, ADMA
levels were significantly higher in subjects with arterial
insufficiency (63.4%) than in men with venous leakage
alone (36.6%).
There was high significant reduction in both ADMA
and LDL level after 6 weeks atorvastatin treatment and
significant improvement in IIEF score, However no
significant change in testosterone level. Six patients
showed severe ED by IIEF score reduced to only one
patient after treatment.
Based on our study we recommend that ADMA
must be considered an important marker for erectile
dysfunction and generalized vascular disease.Also
atorvastatin is an important choice for treatment of erectile
dysfunction in both normolipidemic and hyperlipidemic.