الفهرس 
AcknowledgmentOnly 14 pages are availabe for public view
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Abstract
Salmonellosis is one of the most important bacterial diseases affecting poultry. Its importance is derived from the loss in productivity in affected birds and the hazard it causes for public health. Vaccination is the best mean for controlling salmonellosis in birds. In the present study the immunizing and protective efficacy of local strains (Salmonella Typhimurium, Salmonella Enteritidis and Salmonella Kentucky) in a prepared polyvalent formalin inactivated oil adjuvant vaccine and imported commercial one had been studied. A total of 1080 chickens were divided into 9 groups; groups were vaccinated with the polyvalent locally prepared vaccine, groups were vaccinated with the imported commercial one and group was kept unvaccinated as a control group. The groups were challenged with virulent Salmonella Typhimurium, Salmonella Enteritidis and Salmonella Kentucky strains 1x108 CFU/ml via intramuscular route, 3 week post-vaccination. The degree of protection was assessed according to the severity of the clinical signs and the mortality of the challenged birds. Blood samples were collected weekly and humoral immune response was measured against Salmonella strains using ELISA. In Conclusion: the locally prepared polyvalent Salmonella vaccine induced higher protection rates in challenge test with higher antibody response compared with the imported one.