الفهرس 
IntroductionOnly 14 pages are availabe for public view
 |  | from | 127 |  |  |
| | | from | 127 | | |
Abstract
This study was conducted to investigate the dental and oral health status and its impact on the quality of life (OHRQoL) in children with β-Thalassemia major compared with their normal counterparts.
A total number of 105 (53 in the β-TM group and 52 in control group) aged (2-14) was selected from Hematology Clinic of the Children’s Hospital, Faculty of Medicine, Ain Shams University. Children were selected according to inclusion criteria and after approval and acceptance of their parents, they underwent to the following respectively:
I. Verbal interview about demographic data, medical and dental history beside reviewing the health system files,
II. An intraoral examination by using disposable dental mirror and blunt explorer.
III. Filling out OHRQoL questionnaires.
IV. Receiving oral health educational session
The intraoral examination was done to:
1. Assess the molar relationship using Angle classification.
2. Assess presence of dental caries using DMFT index for
permanent teeth, deft for mixed dentition and dmft for primary teeth.
3. Assess oral hygiene by presence of debris and calculus using OHI-S.
After that the sample was divided into three age groups in accordance with the three different types of OHRQoL questionnaires:
1. (ECOHIS) for ages 2–7 years old (18 β-TM and 21 controls)
2. (CPQ)8-10for ages 8–10 (23 β-TM and16 controls)
3. (CPQ)11-14-SF16 for ages 11–14 (12 β-TM and 15 controls)
The participants and their caregivers were asked to completely fill the questionnaires and at the end they were educated about importance of oral care, correct way of teeth brushing and given oral car instructions leaflet, tooth paste and brush. The collected data was revised, coded, tabulated and introduced to a PC using Statistical package for Social Science to be processed and analyzed.
According to our results the majority of participant were from Cairo also there were significant difference in the level of education of children father’s with majority of illiterate in control group.
Intraoral examination showed class II malocclusion was significantly higher in thalassemia than control. Thalassemia group in mixed dentition (deft) have significantly higher level of dental caries than control group. Oral hygiene level was significantly worse in thalassemia group than control.
The results showed that the total scores of OHRQoL questionnaires and its domains (except the emotional aspect) were not significantly different between thalassemia and controls which means that the oral health status in β-TM patients has no negative impact on their QoL except the higher impact on emotional wellbeing aspect in adolescent children (11-14 age thalassemia group) .
Conclusion
Based on the our findings we concluded the following :
1. Class II malocclusion and dental caries level were higher in thalassemia than control children.
2. Children with β-thalassemia major have worse oral hygiene levels than controls.
3. The oral health status in the adolescent thalassemia group has negative impact on their emotional wellbeing aspect and there is no negative impact of thalassemia itself on OHRQoL.