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العنوان
Effect of Metformin and Mulberry leaves Extract on Male Diabetic Rats /
المؤلف
Ahmed, Diana Abdelbadie Elsaghir Ahmed Abdelfattah.
هيئة الاعداد
باحث / ديانا عبدالبديع الصغيرأحمد عبدالفتاح أحمد
مشرف / أحمد عبده سعيد
مشرف / حسني عبدالفضيل ابراهيم
مشرف / محمد محمود حمزة.
الموضوع
Veterinary Pharmacology. Rats.
تاريخ النشر
2019
عدد الصفحات
164 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
البيطري
تاريخ الإجازة
1/1/2019
مكان الإجازة
جامعة الزقازيق - كلية الطب البيطرى - الفارماكولوجيا
الفهرس
Only 14 pages are availabe for public view

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Abstract

The present study was carried out to investigate the anti-diabetic effect of mulberry leaves and mulberry leaves with metformin on STZ and NA induced diabetic rats [in a rat model of type 2 diabetes (T2D)]. Fifty male albino rats, three months old were allocated into five equal groups each of ten rats.
Induction of diabetes mellitus type II:
The rats received a single intraperitoneal injection of streptozotocin (STZ) (55 mg/kg body weight) 15 minutes after the administration of nicotinamide (110 mg/kg body weight) intraperitoneally.
Control group (Negative control):
Rats received 1ml normal saline orally once daily for 21days.
Diabetic group:
The rats received a single intraperitoneal injection ofstreptozotocin (STZ) (55 mg/kg body weight) 15 minutes after the administration of nicotinamide (110 mg/kg body weight) intraperitoneally.