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العنوان
Comparative study between laparoscopic sleeve gastrectomy (LSG) and laparoscopic mini gastric bypass (MGB) as a potential for cure of type 2 diabetes mellitus/
المؤلف
Ahmed, Ahmed Mohamed Yousry.
هيئة الاعداد
باحث / احمد محمد يسري احمد
مناقش / عادل أحمد أبو نصر
مناقش / إبراهيم جلال إبراهيم
مشرف / حسام الدين أبو الفتوح حساب
الموضوع
Surgery. Diabetes. Stomach.
تاريخ النشر
2019.
عدد الصفحات
107 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
جراحة
تاريخ الإجازة
18/4/2019
مكان الإجازة
جامعة الاسكندريه - كلية الطب - Surgery
الفهرس
Only 14 pages are availabe for public view

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from 154

Abstract

Type 2 diabetes mellitus has now reached epidemic proportions. The latest International Diabetes Federation IDF atlas in 2018 estimates that diabetes in 2017 affected 425 million people worldwide, and it is expected to affect 629 million by 2045. According to new 2018 prevalence data, another 352 million people are estimated to have pre-diabetes.
Although diabetes is considered a chronic disease, treatable with careful diet monitoring, oral treatment, and may be daily injections of insulin, even the most accurate therapy cannot reproduce the precise metabolic control present in the non-diseased state.
T2DM is a risk factor for vascular damage with both micro-vascular (retinopathy; nephropathy and neuropathy predisposing to diabetic foot infections and possibly amputations) and macro-vascular complications (premature and more extensive cardio-, cerebro- and peripheral vascular diseases). Premature mortality and morbidity in diabetes result from such complications.
Reduction of complications of T2DM with tight control of hyperglycemia has been reported, but current therapies, including diet, exercise, behavior modification, oral hypoglycemic agents, and insulin, rarely return patients to euglycemia.
T2DM is a chronic and progressive disease associated with insulin resistance and progressive deterioration of pancreatic beta-cell function, while medical cure for T2DM does not exist, for patients undergoing metabolic surgery; mild or moderate T2DM is a reversible disease.
It has been over 10 years since the resolution of T2DM was observed as an additional outcome of surgical treatment of morbid obesity. Moreover, it has been shown unequivocally that diabetes-related morbidity and mortality have declined significantly postoperatively, and this improvement in diabetes control is long lasting.