الفهرس 
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Abstract
Behçet’s illness is an inflammatory disorder characterised by recurrent attacks influencing the mucocutaneous tissues, eyes, joints, blood vessels, brain and gastrointestinal tract. It is a multifactorial illness classified as a variable vessel vasculitis.
Mature microRNAs are a categery of naturally occurring, tiny non-coding RNA molecules, about nineteen–twenty two nucleotides long. MiRNAs are partially complementary to 1 or more messenger RNA (mRNA) molecules, and their main role is to downregulate gene expression in different ways, including translational repression, mRNA cleavage, and deadenylation.
MiRNA elimination researches have found a main function in the regulation of the immunological response. The elemination of microRNA-155 inhibited T and B cell differentiation in germinal centers, and highly diminished antibody and cytokine production.
In people microRNA-155 is encoded by the microRNA-155 host gene, located on chromosome twenty one. MiR-155 has a role in immunological system particularly in hematopoietic cells upon virus or bacterial infection. The aim of the present work is to study the role of microRNA 155 as a molecular biomarker in Behcet’s disease.
The final result was that miR-155 expression was significantly downregulated in Peripheral blood mononuclear cells from Behcet’s patients with active disease compared to that in the healthy control.