الفهرس 
Intoduction
The causative agentOnly 14 pages are availabe for public view
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Abstract
The current study was carried out to determine the prevalence of Theileria annulata infection in both large and small ruminants in Al-Ghaniem Region, Assiut Governorate, Egypt, from April 2015 to April 2018, with an evaluation of the important factors affecting the epidemiology of the disease. The study also included some pathological changes that occur on the infected animal with a diagnostic study of the Theileria parasite using PCR.
The study included clinical examination of 300 cows of different ages and species of both sexes, randomly collected from the Ghanayem region, Assiut Governorate. In addition, 100 buffalos were examined clinically from different ages and species, whether individual or in contact with the cows in the same place of breeding In addition to , 100 (70 sheep and 30 goats) were in contact with positive cases of cattle and buffalo. 60 cows and 10 buffalos showed clinical signs of fever with ticks on the animal body , with enlarged lymph nodes and eye opacities icteric of visible mucous membranes , associated with respiratory signs and diarrhea in some cases, but neither sheep nor goats showed clinical signs
An autopsy was carried out for six cases 4r females and 2 males. It was found that the animal was suffering from general wasting, enlarged lymph nodes, lung eodema and exudates , enlarged spleen, ulcers of the fourth stomach, and liver enlargements in some cases with distended gall bladder.
Blood studies showed a high level of parasite in the blood 75% in the cattle and 66.76% in the buffalo respectively and all blood smears taken from the sheep are negative. For the lymphatic stage for the cows was 43.33% the importance of blood smears to detect acute cases, butit was found that, the PCR technique was highly specific in the diagnosis of theileriosis. In chronic cases, which is difficult to diagnosed by blood film .Control of Ticks is the backbone in controlling of Thieleriosis and other hemoprotozoal diseases. Spraying insecticides periodically to eliminate the vector of disease and fill cracks and openings in animal pens.