الفهرس 
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Abstract
Atopic dermatitis is the most common chronic inflammatory skin disease affecting children worldwide. Skin barrier defect, impaired innate immunity, and absence of allergens sensitization may explain their high susceptibility to skin infections mainly by S.aureus which in most times is methicillin resistant (MRSA). Our study aimed to detect S.aureus colonization, identify MRSA from skin and nose of AD children and determine their antimicrobial susceptibility. Three swabs were taken from nose, skin lesion, and antecubital fossa in patients and 2 swabs from nose and antecubital fossa in controls. All samples were processed in Microbiology Diagnostic and Infection control Unit. Isolation, Identification of bacteria and antibiotic sensitivity tests were done. Our study included 50 AD children their ages ranged between 3months and 12 years and they were 30 males and 20 females as a study group. Fifty healthy children were included as a control group. High prevalence rate of S.aureus (90%) and MRSA (18%) colonization from the nose and/or skin of AD children was detected. Although a high rate of MRSA was detected among patients with moderate and severe SCORAD, the relationship between rate of MRSA colonization and AD severity was not statistically significant. This may be related to the small number of patients included in our study. All MRSA strains were sensitive to vancomycin howevere, they showed high resistance rates for gentamicin, imipenem, amoxacillin-clavulinic, fusidic acid, levofloxacin, cephalexin, pipracillin, and cefuroxime.