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Abstract SUMMARY AND CONCLUSION Malignant biliary obstruction has a grave prognosis and severe adverse effect on the quality of life, with most of those patients are inoperable at time of diagnosis. So, palliative biliary drainage became the main line of treatment of those patients. Interventional radiology provides many minimally invasive procedures to alleviate symptoms of biliary obstruction. Demonstration of the role of interventional radiology in treatment of malignant obstructive jaundice was the aim of our study. In this study, 30 patients with malignant biliary obstruction, 28 of them was non surgically curable and the other two patients were fit for operation with post-operative biliary complications were subjected to many interventional techniques to drain the obstructed bile, 10 of our patients underwent percutenous external drainage, 3 patients underwent internalexternal drainage and 2 patients with help of a guide wire passed percutaneously (associated with endoscope session) through the dilated intrahepatic biliary radicals then passed through the ampulla of the duodenum (Randez. Vous technique). Eight patients underwent metallic stent insertion and 7 with plastic stent insertion. In the patients who were fit for operation (whipple) with postoperative choledecho-jujenostomy biliary stricture, metallic stenting showed high success rate in reduction of bilirubin level and its related complications. Significant bilirubin reduction was achieved in 13 from the 15 percutenously stented patients (86.6%), in 10 from the 13 percutaneously drained patients ( including external only and internal external route) (76.9%) |