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العنوان
Serum Bilirubin As a predictor of Coronary Artery Disease Severity in Patients Undergoing Primary Percutaneous Coronary Intervention /
المؤلف
Elmalla, Mohamed Asem Ali.
هيئة الاعداد
باحث / محمد عاصم علي الملا
مشرف / طارق صلاح خليل
مشرف / وليد عبده ابراهيم
الموضوع
cardiology. Bilirubin.
تاريخ النشر
2019.
عدد الصفحات
97 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض القلب والطب القلب والأوعية الدموية
تاريخ الإجازة
10/7/2019
مكان الإجازة
جامعة المنوفية - كلية الطب - امراض القلب والاوعية الدموية
الفهرس
Only 14 pages are availabe for public view

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from 110

Abstract

For a long time, the bile pigment bilirubin was considered a toxic waste product formed during heme catabolism. However, more recent evidence suggests that bilirubin is a potent physiological antioxidant that may provide important protection against atherosclerosis, coronary artery disease (CAD), and inflammation (Mylonas & Kouretas, 1999)
Several mechanisms have been suggested to play a potential role in the anti atherogenic and cardio protective effects of bilirubin as ; bilirubin mediated inhibition of lipid oxidation, Bilirubin as a reflection of enhanced heme oxygenase (HO) activity and An involvement of bilirubin in immune reactions and inflammatory processes has also been documented (Mayer,2000).
Most studies of TB and CAD have focused on stable CAD. Few studies have focused on the relation between the serum TB level during acute stress and the short- and long-term clinical outcomes like Okuhara et al., 2010.
Aim of the work is to evaluate the relationship of serum bilirubin level with the severity and complexity of coronary artery disease (CAD) in the patients undergoing primary percutaneous coronary intervention (PCI).
The present study is a prospective, cross sectional observational study compromised of 70 patients categorized into 43 males (61%)..27 females (39%) admitted with STEMI who underwent primary PCI then admitted to CCU for follow up. Their ages range from 30 to 75 years old with mean age 52.5 years old.