الفهرس 
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Abstract
The present study was conducted to evaluate the possible protective effect of curcumin or ginger against paracetamol induced hepatotoxicity as a prophylactic agents in comparison to standard drug silymarin.
Experimental design
During this study, a total number of 45 apparently healthy male albino rats were divided into 9 equal groups, each of 5 rats.
group 1: was given distilled water (1 ml/kg b.wt) and kept as a control.
group 2: was administered tween 80 at a dose of 2.5 ml/kg b.wt orally once daily for 15 successive days.
group 3: was administered silymarin at a dose of 200 mg/kg b.wt orally once daily for 15 successive days.
group 4: was administered curcumin at a dose of 200 mg/kg b.wt orally daily for 15 successive days.
group 5: was administered ginger extract at a dose of 200 mg/kg b.wt orally once daily for 15 successive days.
group 6: was administered paracetamol at a dose of 500 mg/kg b.wt orally once daily for the last 5 successive days (from 11th day until 15th day).
group 7: was administered silymarin (200 mg/kg b.wt) orally once daily for 10 successive days and simultaneously with paracetamol (500 mg/kg b.wt) for the last 5 successive days.