الفهرس 
Traumatic Brain Injury
Inclusion criteriaOnly 14 pages are availabe for public view
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Abstract
Brain midline shift (MLS) in traumatic brain injury is a life-threatening condition that requires urgent
diagnosis and treatment. The early detection of a MLS in severe traumatic brain injury patients is thus very
important because it allows starting an appropriate treatment plan. Head CT is considered to be the gold standard to
diagnose MLS. Transcranial B-mode sonography (TCS) is a bedside neuroimaging technique which is safe, painless,
and accurate. The aim of the present study is to monitor the effect of mannitol 20% solutions on brain mid line shift
by using transcranial ultrasonography in severe traumatic brain injury. The current study is a prospective
observational study conducted on 30 adult male and female admitted to the Critical Care Medicine Departments in
Ain Shams University Hospital with the diagnosis of severe traumatic brain injury. In the current study, there was a
positive correlation between APACHE II and ICU stay and mortality. We also found that brain edema, midline shift,
Glasgow coma score and FOUR score were improved after the use of mannitol 20% solution. The most important
finding in this study was that transcranial ultrasonography can detect and monitor MLS with only a small difference
in comparison to CT brain so it provide a cheap accurate noninvasive and bedside tool for diagnosis and monitoring
MLS.
[Mohamed Anwer Elshafey, Ghada Mohamed Samir, Riham Fathy Galal, and Ahmed Metwally Mahmoud
ElAtrash. Monitoring the Effect of Mannitol 20% Solution on Brain Midline Shift Using Transcranial
Ultrasonography in Severe Traumatic Brain Injury. Nat Sci 2019;17(5):78-88]. ISSN 1545-0740 (print); ISSN
2375-7167 (online). http://www.sciencepub.net/nature. 9. doi:10.7537/marsnsj170519.09.