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Abstract Worldwide, 130-170 million persons are living with chronic hepatitis C virus (HCV) infection, which, if left untreated, can result in cirrhosis and liver cancer. Egypt has the largest burden of HCV infection in the world, with a 10% prevalence of chronic HCV infection among persons aged 15-59 years (The GlobalBurden of Hepatitis C. , 2004).HCV transmission in Egypt is associated primarily with inadequate infection control during medical and dental care procedures. ( El Zanaty . ,2012) ( Paez and Jimenez, 2009). In response, the Egyptian Ministry of Health and Population (MOHP) in 2001 implemented a program to reduce health care associated HCV transmission and in 2008 launched a program to provide care and treatment. ( Paez Jimenez . , 2010). The highest HCV prevalence in the world occurs in Egypt, where the prevalence of infection increases steadily with age, and high rates of infection are observed among persons in all age groups ( Abdel Aziz. ,2000).This pattern indicates an increased risk in the distant past followed by an ongoing high risk for acquiring HCV infection, although there are regional differences in average overall prevalence (Medhat . , 2002). Child- Pugh scoring, the score employs five clinical measures of liver disease. Each measure is scored 1-3, with 3 indicating most severe derangement. The consists of Total bilirubin, Mmol/1 (mg/dl), Serum albumin, g/dl, PT INR, Ascites and Hepatic encephalopathy (Chologitas et al ., 2005).Chronic liver disease is classified into Child- Pugh class A to C, where score 5-6 is class A, Score 7-9 is class B and score 10-15 is class C. (Chologitas et al . , 2005). |