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Abstract Cranioplasty carries a high risk of post operative complications, Infection and bone resorption are the most common. -Infection was found to be associated significantly to type of the material used in cranioplasty ”bone cement is the most significant” and time interval between craniectomy and cranioplasty ” infection is associated with early cranioplasty” . - Bone flap resorption is a key complication after cranioplasty using autologous bone flaps. Young age and bone fragmentation are risk factors for reoperation. So, a primary synthetic implant is recommended in cases with fragmented bone flap, delayed time of cranioplasty (>3 months) or in patients younger than 30 years of age. - Methyl methacrylate (bone cement) is cheaper than titanium mesh and is easy to contour and remodel giving a better cosmetic result, but it carries higher risk of infection and is less protective to the cranial contents. -Titanium mesh has good protective function and less risk of infection than bone cement , cosmetic result is acceptable in most cases and can be improved according to the surgeon’s experience. - Medpor has excellent results functionally and cosmetically especially in small and medium sized skull bone defects and in craniofacial reconstruction. However, high cost limits its use especially in poor countries. |