الفهرس 
Breast Cancer
Ductal carcinoma in situ (DCIS):Only 14 pages are availabe for public view
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Abstract
Summary
Breast cancer is the most common cancer in women and the second most
common cancer globally. Breast cancer is also one of the leading cause of
cancer death among women worldwide.
Pleiotrophin (PTN), is a heparin binding growth-associated molecule has
a high affinity for heparin and is approximately 45% identical to human
Midkine. It showed high expression related to occurrence and development of
many malignant tumors such as: lung cancer, testicular cancer and breast cancer.
PTN help in staging of tumor, the more the level of PTN in serum the
more the stage of tumor.
The aim of the present work is to study the potential role of Pleiotrophin
as a biomarker in breast cancer patients.
This study was carried out on 60 female breast cancer patients whose age
ranged from (29 to 78) selected from the oncology department Tanta university
& 20 healthy female whose age ranged from (30 to 61).
The studied subject divided into two groups:
group I: 20 healthy subjects without an evidence of malignant disease.
group II: 60 female breast cancer patient.
All patients will be subjected to the following:
1. Complete history including:
Personal data as name, age, marital status, menstrual history, address,
parity, special habit as smoking and occupation.
History of breast cancer (Onset, Duration, Severity, Progression)
Family history of breast cance