الفهرس 
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Abstract
The present study was carried out to study the effect of Ginsing as antioxidant against steroid induced osteoporosis and osteonecrosis and the main role of the oxidative stress.
Fourty mature male New Zealand white rabbits, 20 weeks old, average body weight of 1.5 - 2 kg. B.Wt. obtained from the Laboratory Animal Farm of Faculty of Veterinary Medicine, Zagazig University. Rabbits were healthy and pathogen-free. The animals received a standard laboratory diet and water ad libitum.
Two separate experiments were conducted, one for acute model and the second for chronic model. In acute experiment, the duration of the experiment is only one week. Twenty male rabbits were divided into four equal groups, each of five. group (I) (Control group) Kept without any medications. group (II) (Steroid group) injected intramuscularly once into the right gluteal muscle with 20mg/Kg. B.Wt of methyl prednisolone. group (III) (Steroid + Ginseng group) treated with both methylprednisolone once a week and Ginseng given orally, daily for 7 days. group (IV) (Ginseng group) given Ginseng alone orally for 7 days.
In chronic experiment, the duration of this experiment is 6 weeks. Twenty male rabbits were divided into four equal groups, each of five. group (I) (Control group) kept without any treatment. group (II) (Steroid group) injected intramuscularly once weekly into the right gluteal muscle with 4mg/Kg. B.Wt of methyl prednisolone. group (III) (Steroid + Ginseng group) treated with both methylprednisolone once a week and Ginseng given orally, daily for 6 successive weeks. group (IV) (Ginseng only group) given Ginseng alone orally for 6 weeks.