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العنوان
Structure Elucidation and Biological Evaluation of
Active Chemical Constituents Isolated from Some
Medicinal Plants /
المؤلف
Mahmoud, Hazem Ali Al-Badry.
هيئة الاعداد
مشرف / محمد طاهر محمد الوسيمي
mohamed_elwasami@science.sohag.edu.eg/
مشرف / صبرى حمدى حامد يونس
sabry_younas@science.sohag.edu.eg/
مشرف / محمد طاهر محمد الوسيمي
mohamed_elwasami@science.sohag.edu.eg/
مشرف / صبرى حمدى حامد يونس
sabry_younas@science.sohag.edu.eg/
الموضوع
Organic Chemistry.
تاريخ النشر
2019.
عدد الصفحات
378 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
Organic Chemistry
تاريخ الإجازة
29/7/2019
مكان الإجازة
جامعة سوهاج - كلية العلوم - الكيمياء
الفهرس
Only 14 pages are availabe for public view

from 484

from 484

Abstract

The present work deals with phytochemical studies for
important plants under the title ”Structure Elucidation and
Biological Evaluation of Active Chemical Constituents Isolated
from Some Medicinal Plants’’.
Artimisia sieberi (Asteraceae) and Moringa oleifera (leaves
and seeds), fresh plants material were air dried and ground to fine
powder. The ground materials were transferred to a suitable flask
and soaked in MeOH-CH2Cl2 (1:1) for 24 hours at room
temperature. The extracts were evaporated under reduced pressure
to give an oily residue.
The residue of Artimisia sieberi was submitted for
fractionation by column chromatography on silica gel eluted with nhexane and dichloromethane, then with dichloromethane–methanol,
with increasing polarity. Repeated column chromatography (CC)
over silica gel using CH2Cl2–EtOAc and CH2Cl2–MeOH mixtures
and TLC over silica gel using the preceding mixtures, to give pure
compounds.
The purities of all isolates (> 95.0%) were analyzed by
HPLC. The structures of the isolated compounds were confirmed
using (EI-MS, 1H-NMR, 13C-NMR, DEPT, 1H1H COSY, HMQC
and HMBC) and compared with literature data.