الفهرس 
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Abstract
This study was an interventional study, with a controlled clinical trial design in which individual subjects are assigned to either isotretinoin or conventional acne therapy. It was carried out on 63 patients of both genders who were diagnosed with moderate acne vulgaris and those who attended the Dermatology Outpatient Clinics in Suez Canal University hospitals, Ismailia. The main objective was to assess quality of life and the clinical improvement in patients with moderate acne vulgaris when treated with isotretinoin compared to those treated with conventional therapy.
Patients were enrolled and answered the quality of life questionnaires at the beginning of the study and the baseline visit measurements were taken prior starting therapy. On the baseline visit, photo documentation, acne assessment and scoring. And prescription were either standard conventional therapy (Standard therapy consists of topical retinoid plus benzoyl peroxide and oral doxycycline) or oral isotretinoin.