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Abstract Background: Patients follow up subsequent to conservative breast therapy (BCT) is essential due to tumor recurrence with rates ranging between 1% and 2% annually. It occurs commonly during a period of 3–7 years after being subjected to BCT. Timely and early detection of breast cancer recurrent is believed to remarkably improve and assist long-term survival. Aim of the Work: to assess new advances of magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) in diagnosis of recurrent breast cancer after conservative surgery, chemotherapy and radiotherapy and differentiate it from post therapeutic changes. Patients and Methods: The current study was conducted on 20 patients with malignant breast lesions detected by histopathological grading. Fourteen patients were presented with breast lump, six patients were presented by nipple discharge at El Demerdash hospital during the period from October 2018 to April 2019. Results: A strong positive correlation is detected between choline peak findings and the level of Ki67, the higher the choline the higher the Ki67 the more aggressiveness is the tumor. Conclusion: Both dynamic contrast enhanced MRI and MRS are valuable tools in the evaluation of postoperative breast having high sensitivity and specificity to differentiate between benign postoperative changes and recurrent malignant tumor. On the other hand, MRI on the breast can assist to avoid unnecessary interventions and optimizes diagnosis of recurrence in its early stages. |