الفهرس 
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Abstract
The present study aimed to detect the expression of SOCS3 in lichen planus of diseased patients as compared to normal control persons.
Results of the present study showed that (53.3%) of the LP cases were none –smokers while (46.7%) were smokers. (93.33%) were male; (6.67%) were female.
Regarding the disease duration, (66.7%) of LP cases had progressive disease course while (33.3%) had stable disease course.
In our study, the majority (96.7%) had classical form of the disease. Regarding the distribution of lesions, (60%) had generalized form of the disease and (20%) had generalized and oral form.
In the present study, the disease duration was 11 ± 11 (1 – 48).
Relation between SOCS3 and categorical variables in LP cases were studied in the current study. There were strong relation between SOCS3 and gender; smoking; and distribution of lesions. There was weak relation between SOCS3 and type of the disease and course of the disease.
In the current study, there was very weak relation between SOCS3 and duration of the disease and patients age.
Results of the present study showed statically significant relation between cases and control regarding gender, highly statically significant relation between cases and control regarding SOCS3, In the present study, there was none statically significant relation between cases and control regarding age.
In our study, LP cases and control were compared using SOCS3; to determine the cut-off value, we performed a ROC analysis. SOCS3 has perfect value for discrimination between LP cases and controls with an area under the ROC curve of 1.0 (95% CI = 0.940 to 1.000, P-value <0.0001). Best cut-off is a value of 1.5 (sensitivity = 100%, specificity = 1.0, J-index = 1.0).