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Abstract The most commonly used folate antagonist is methotrexate where it is effective in many malignancies. Breast, head and neck, colorectal, non-Hodgkin’s lymphomas, osteosarcoma,bladder and choriocarcinoma.This study was conducted to examine the possible modifying effects of Ginkgo biloba against hippocampal and brain toxicity induced by methotrexate in male albino rats. This could be fulfilled through the histological, immunohistochemically and biochemical analysis of hippocampal brain tissues |