الفهرس | Only 14 pages are availabe for public view |
Abstract This thesis includes applying the cyclic voltammetry technique in 0.1M KCl with the use of the gold electrode as a working electrode to study the redox behavior for SeO2 in the absence and presence of ligands (Succinic acid and Dithizone), copper bromide in the absence and presence of Succinic acid. Also, the study of CdCl2 in the absence and presence of EPTC ligand in 0.1M KCl. This study was performed with the regard of the temperature. The results obtained were used to calculate the diffusion coefficients, rate of electron transfer constant, surface coverage, amount of cathodic and anodic electricity as well as thermodynamic parameters like stability constant and Gibbs free energy. The copper and cadmium complexes were prepared separately by 1:2 (metal: ligand) for copper and 1:1(metal: ligand) for cadmium. The formation of the complexes was affirmed by performing various measurements and analyses. The theoretical studies of the molecular modeling for the prepared complexes were carried out by applying DFT calculations by Materials studio. The results demonstrated the stability and the activities of the complexes. Finally docking of the EPTC ligand with the human colon cancer antigen (2hq6) and the human liver cancer (3cmf), results showed that the interaction between the EPTC ligand with the human colon cancer antigen (2hq6) is preferred than the interaction between the EPTC ligand with the human liver cancer (3cmf) according to the data of binding free energy and Ki. |