الفهرس 
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Abstract
On a worldwide scale, chronic hepatitis B virus (HBV) infection can lead to advanced liver disease including cirrhosis and hepatocellular carcinoma (HCC). Studies have shown that sustained HBV clearance reduces the risk of disease progression, but it is unclear whether HBV DNA levels in patients with persistent viremia is associated with disease severity. This is an important consideration, because viral load could potentially be used to guide decisions about when to start treatment.
Fibro Scan has been considered as a rapid and non-invasive method to assess liver fibrosis in patients with chronic hepatitis B (CHB).
This was a descriptive study in which 100 patients diagnosed to have chronic HBV. Liver stiffness using FibroScan measured in Kilopascal is used to assess degree if fibrosis divided it into 2 groups.
group A with chronic hepatitis B infection with non-advanced fibrosis and group B with chronic hepatitis B infection with advanced fibrosis. In the study, Sex distribution showed male predominance, for most of the referred patients.
In the current study; there was a significant difference between fibroscan and AST thus, the more the degree of fibrosis by fibroscan, the higher the AST also there was a highly significant difference between fibroscan and serum Albumin, INR, total bilirubin and platelet.
There was no significant difference between studied groups regarding serum ALT, direct bilirubin & AFP.
In the present study, our results showed that HBV PCR was non-significantly higher among cases with than without cirrhosis and that HBV PCR had no significant diagnostic performance in differentiation between fibrosis stages.
In clinical practice, such results could be of major relevance for follow up of patients with cirrhosis. Our study strongly suggested that liver stiffness measurements and HBV viral load were not correlated to each other’s, they are both mandatory for assessing degree of liver fibrosis & degree of viraemia.