![]() | Only 14 pages are availabe for public view |
Abstract Summary The study was designed with the objective of comparing the effect of Streptokinase-based pharmacoinvasive strategy as opposed to primary angioplasty in patients with STEMI on left ventricular systolic function by measuring Global and regional longitudinal strains using 2- D speckle tracking echocardiography at cardiology department, Tanta University. The study was conducted on 50 patients that were divided into 2 groups. group 1 consisted of 25 patients that had primary PCI as a reperfusion therapy & group 2 consisted of 25 patients who had thrombolytic therapy followed by coronary angiography with possibility for PCI. In the second group, coronary angiography was done within 3 – 24 hrs. It was shown that primary angioplasty fares better than streptokinase-based pharmacoinvasive strategy in terms of post revascularization LV function which is a strong predictor of adverse outcomes, even in patients without failure or shock at presentation. Given the fact that 80% of the patients in the pharmacoinvasive arm had patent culprit vessel with TIMI III 3 flow at the time of angiogram, it is possible that the benefits of primary angioplasty extend beyond those attributable to the re-establishment of flow in the culpri |