الفهرس 
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Abstract
Introduction : Partial pulpotomy is a vital treatment for carious and traumatic exposure, especially in young permanent teeth. This study evaluated the healing capacity of autologous bone marrow– mesenchymal stem cells (BMMSCs) on partially pulpotomized teeth in a dog model.Methods : Twelve mongrel dogs were selected, and a total number of 192 posterior mandibular and maxillary teeth were involved in the study (16 teeth per dog). Partial pulpotomies were performed, and the dogs were assigned into 2 equal groups (groups I and II), 6 dogs in each group. The coronal pulp cavities (n = 96) of group I were capped with calcium silicate–based capping material. group II coronal pulp cavities (n = 96) were seeded with 1 * 105 cell/Ml BMMSCs, and then the cavities were capped with calcium silicate–based capping material. After placing the capping materials, the cavities of both groups (I and II) were filled with resin-modified glass ionomer restorative material. from each group, 48 teeth from 3 dogs were evaluated histologically after 1 week, and the other 48 teeth from the remaining 3 dogs were evaluated after 9 weeks. Scoring was done for the amount of inflammatory cell infiltrates, tissue necrosis, and thickness of hard tissue bridge formation.Results : The Mann-Whitney U statistical test performed for hard tissue bridge formation revealed significant differences between the 2 groups at the 1- (P < .05) and 9- week (P < .05) examination periods.Conclusions : Autologous BMMSCs have significant therapeutic potential because they enhance the healing capacity of partially pulpotomized dogs’ teeth.