الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
The incidence of breast cancer worldwide is increasing, and with more sophisticated imaging modalities and screening programs, the incidence of small non palpable breast cancers is increasing as well. So, the detection of breast nodules for diagnosing cancer precursor lesions before clinical manifestations is essential, considering its early discovery allows a less aggressive treatment and yet more effective for these diseases.
The aim of our study is to assess the diagnostic value of US guided biopsy in patients with suspicious non palpable breast masses detected sono-mamographycally by correlation of histo-pathological results of US guided biopsy with those obtained after post-operative excision of these non palpable masses .
Our results yielded a high sensitivity of 95.1% with 100% specificity, and a PPV, NPV, and DA of 100%, 97.2%, and 98.2%, respectively. In fact, there were no false positive results. It means that tru-cut biopsy (TCB) provides a breast cancer diagnosis with a high degree of confidence.
Our study revealed that Tru-cut biopsy is an accurate diagnostic tool of suspicious non palbable breast masses with a high diagnostic accuracy of 97.5% as it supplies enough tissue for pathologists to establish a correct histological assessment. So It is a preferable procedure for the diagnosis of breast lesions prior to operation rendering to its low cost, high accuracy,minimal complications,safe and short time procedure.
Also it can save a lot of expenses and unnecessary surgical procedures and lessens the propensity of complicated surgical procedures and minimizes patient stress with benign lesions. In patients with malignant lesions, in addition to having diagnostic significance, TCB also provides adequate tissue for the evaluation of molecular markers which have extreme therapeutic value. Therefore, we propose that TCB is an accurate diagnostic procedure for breast lesions.