الفهرس 
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Abstract
Background: chronic obstructive pulmonary disease (COPD) is a disease state characterized by progressive airflow limitation and is associated with an abnormal inflammatory response of the lungs to noxious particles or gases, primarily caused by cigarette smoking.
Objectives: Assessment of the pulmonary functions in chronic Obstructive Pulmonary Disease patients with normo-glycemia, chronic Obstructive Pulmonary Disease with diabetes mellitus and diabetes mellitus patients.
Patients and Methods: The present study was a case-control study conducted upon sixty patients from Outpatients and Inpatients at the departments of Chest Diseases and Internal medicine in Ain Shams University and Specialized Hospitals divided into 3 groups: twenty patients with diabetes mellitus, twenty patients with COPD and twenty patients with both COPD and diabetes mellitus.
Results: There was highly significant statistical difference found between the three studied groups regarding pulmonary function test parameters including FEV1/FVC, FEV1, FVC, and MMEF50 recording the lowest values among the COPD diabetic patients. DM is associated with pulmonary function affection of 75% of patients in group 1(only diabetic) having mild to moderate restriction and FVC ranges from (64 – 99). There was statistically significant negative correlation found between FEV1 and duration of DM, smoking index (in years) and number of exacerbations in COPD diabetic patients.
Conclusion: Pulmonary function test values were the least in COPD diabetic patients, pulmonary function test values were reduced in DM independent of smoking, reduced lung functions in patients with diabetes is inversely related to blood glucose levels, duration of diabetes and is independent of smoking or obesity.