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Abstract Fifty samples of fish were collected from Wadi El-Rayan, Fayoum governorate, Egypt. The samples represented by O. niloticus lake I, O. niloticus lake II, farmed Oreochromis niloticus, Bagrus bajad lake I and Sea bass lake II (10 samples of each). The collected samples were kept in an icebox and transferred directly to the central Laboratory, Faculty of Veterinary Medicine, Zagazig University. Cadmium residues (Cd) The cadmium residues ranged from 0.01 to 0.03, 0.05 to 0.11, 0.01 to 0.03, 0.01 to 0.35 and 0.01 to 0.04 ppm with mean values of 0.023 ± 0.003, 0.083 ± 0.007, 0.023 ± 0.003, 0.083 ± 0.045 and 0.025 ± 0.003 ppm for examined O. niloticus lake I, O. niloticus lake II, Farmed O. niloticus, B. bajad lake I and Sea bass lake II, respectively. A positive Pearson correlation between cadmium , lead, mercury, arsenic and copper meanwhile, cadmium negatively correlated with zinc (-0.139).The general acceptability was 34 (68%) acoording to the level of cadmium contamination. The dietary exposure assessment for Cd through fish consumption was carried out by detecting the estimated daily intake in comparison to the tolerable daily intake. The average quantity of fish consumed per adult person (assuming a 70 kg person) every week was 12 ounces (approximately 340 grams weekly 48.57 g/ daily. The estimated daily intake (EDI) of cadmium from all examined fish samples ranged from 0.016 to 0.058 with an average 0.033 µg/ kg body weight/day. The EDI lower than the tolerable daily intake (1 µg/ kg body. |