الفهرس | Only 14 pages are availabe for public view |
Abstract Diazines and Triazines and their derivatives play an important role in medicinal chemistry due to their high biological activity. They are known to possess a broad spectrum of pharmacological activities such as antiviral, antibacterial, fungicidal, insecticidal, herbicides, hypotensive, hypothermic activities, in vitro supporting their anti-HIV, anticancer activities and biological inhibitors. The original work of this thesis can be classified into three parts: Part 1: In this part Synthesis of hydrazino 1,2,4-triazine derivative and its reactions with different reagents to form novel triazine derivatives. Part 2: In this part Synthesis of an acid hydrazide derivative and its utility in building of new hetrocylic systems such as oxadiazole, triazole and pyrazole derivatives. Part 3: The antitumor activities of some of the synthesized compounds were examined against liver and breast cancer cell lines. |