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العنوان
Study the role of right liver lobe diameter by ultrasound/ serum Albumin level ratio in prediction of oesophageal varices in cirrhotic patients /
المؤلف
Metwally, Ahmad Yusuf Hassan.
هيئة الاعداد
باحث / أحمد يوسف حسن متولى
مشرف / محمد علاء الدين نوح
مناقش / نهله السيد الجمال
مناقش / عاطف أبو السعود علي
الموضوع
Ttropical Medicine. Oesophageal Varices. Liver cirrhosis. Liver- Cirrhosis.
تاريخ النشر
2019.
عدد الصفحات
105 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب
تاريخ الإجازة
30/12/2019
مكان الإجازة
جامعة المنوفية - كلية الطب - طب المناطق الحارة وصحتها
الفهرس
Only 14 pages are availabe for public view

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Abstract

This prospective study included two hundred patients with liver cirrhosis selected from the attendance of tropical department of Menoufia University Hospital and Shebin El-Kom Teaching Hospital.
Patients were grouped according to endoscopy finding into two groups:
group 1: Patients with no oesophageal varices.
group 2: Patients with oesophageal varices.
Patients was classified according to Child–Pugh score using 5 parameters (ascites, albumin, bilirubin, prolonged prothrombin activity and encephalopathy) into child A, child B and child C.
Patients with the following criteria were excluded, patients receiving beta blockers, patients with hepatocellular carcinoma, patients with primary hematologic disorders, patients who underwent splenectomy, patients with portal vein thrombosis and patients on regular albumin infusion.
All studied subjects underwent a detailed clinical examination, laboratory workup, abdominal ultrasound and upper gastrointestinal endoscopy.
The right liver lobe diameter/albumin ratio and the platelet count/spleen diameter ratio for all patients were calculated.
The results of this study were as follows:
1. A statistically significant difference is noted between patients with OV and those without OV regarding laboratory data e.g. haematological profile (HB level, PLT count and WBCs count) and liver profile (Bilirubin total and direct, ALT, AST, PT time, INR and Albumin), however no statistically significant difference is noted with kidney functions (creatinine, urea).
2. A statistically significant difference is noted between patients with OV and those without OV regarding radiological parameters e.g. Right lobe diameter, spleen diameter and PV diameter.
3. A statistically significant difference is reported regarding child pugh class and the presence and grading of OV e.g. the more advanced child class of the patient, the more advanced grade of OV he has. Another statistically significant difference is also found regarding child pugh class and bleeding OV risk e.g. the more advanced child class the more risk of bleeding from OV.
4. A statistically significant difference is noted between different grades of OV regarding spleen diameter, PV diameter, Rt. Lobe diameter/albumin ratio and Plt count/spleen ratio. But no statistically significant difference between grades of varices regarding Rt. Lobe diameter alone.